Dr. med. Dr. med. univ. Mathias Roth

2026

Habilitation thesis at Heinrich Heine University Düsseldorf on the topic “Microbial Keratitis in Germany - Epidemiology, Risk Factors, and Modern Diagnostics at a Tertiary Care Center”

2025

Location Manager, YOUSEE Düsseldorf

since 2023

Consultant physician for refractive surgery (PRK, Femto-LASIK)

2021-2023

Care Vision Düsseldorf, Consultant physician for refractive surgery (PRK, LASIK, Femto-LASIK)

since 2018

Hösel ophthalmology practice, founding of private medical practice together with Prof. Dr. Tobias Stupp (until 2024)

since 2018

University Eye Clinic Düsseldorf, Specialist (20% position); Focus: Uveitis, pemphigoid, inflammatory and infectious eye diseases

Since 2017

University Eye Clinic Düsseldorf, Research Associate; Coordinator of the German Fungal Keratitis Registry

2018

North Rhine Medical Association, Düsseldorf; certification as a specialist in ophthalmology

2016-2017

Tausendfensterhaus Eye Clinic, Duisburg (Prof. Dr. Schmidt, Dr. Engineer), Resident Physician

2017

Heinrich Heine University Düsseldorf, Doctorate in Medicine (Dr. med.), summa cum laude

2012-2016

University Eye Clinic Düsseldorf (Prof. Dr. Geerling), assistant physician and research assistant

2012

Greifswald University Eye Clinic (Prof. Dr. Clemens), assistant physician and research assistant

2011

State Office for Health and Social Affairs Mecklenburg-Western Pomerania, Granting of a license to practice medicine in Germany

2005-2011

Medical University of Vienna Studied human medicine, graduating with the title Doctor of Medicine (Dr. med. univ.)

2009-2010

Autonomous University of Madrid, study of human medicine (ERASMUS scholarship), clinical tertials

2020

Basic course and advanced course for investigators/deputies or principal investigators in clinical trials in accordance with the German Medicines Act/EU V 536/201

2016

ICO Basic Science Exam

2014

Sponsors and friends of the University Eye Clinic Düsseldorf e.V.

2013

Further training to become a GenTSV, recognized by the Düsseldorf district government (file number 53.02.01-K-2.3/10)

2012

Animal Experimentation Course (FELASA B equivalent)

2012

German Ophthalmological Society (DOG)

2012

Professional Association of Ophthalmologists (BVA)

2026

Dail YA, et al. Dysregulated Intraocular Pressure in Acanthamoeba Keratitis: Clinical Associations, Therapy, and Prognosis. Microorganisms. 2026;14:1294.

2026

Roth M, Geerling G, Strzalkowski P, Lindhof HH, Guthoff R. Emerging pathogens of ocular infections due to environmental changes—what lies ahead? Die Ophthalmol. 2026;1–6. doi: 10.1007/s00347-026-02434-8

2026

Kourukmas RJ, et al. Heimat oder Ausland? Mögliche Auswirkungen des politischen Wandels in Syrien auf Ärzte in Deutschland. Die Ophthalmol. 2026;1–7. doi: 10.1007/s00347-026-02385-0

2025

Strzalkowski P, et al. Aktuelle Trends bei der Behandlung rhegmatogener Netzhautablösungen und perioperative Lagerungsstrategien in Deutschland: Ergebnisse einer retina.net-Umfrage. Die Ophthalmol. 2025;122:383–392.

2025

Strzalkowski P, et al. Carbon footprint of pars plana vitrectomies in rhegmatogenous retinal detachment in Germany between 2013 and 2023 – A cohort study of fluorinated gas emissions. Graefe’s Arch Clin Exp Ophthalmol. 2025;1–8. doi: 10.1007/s00417-025-06905-7

2025

Holtmann C, Roth M, Beseoglu K, Borrelli M, Geerling G. Corneal Neurotization in Elderly Patients with Multimorbidity. Curr Eye Res. 2025. doi: 10.1080/02713683.2025.2509567

2025

Cieplucha M, et al. Diurnal Variation in Corneal Stromal and Epithelial Thickness in Fuchs Endothelial Corneal Dystrophy: With and Without Intensified Hypertonic Saline Eyedrop Application. Cornea. 2025. doi: 10.1097/ICO.0000000000004041

2025

Roth M, Geerling G. Klimawandel – eine vielseitige Herausforderung für die Augenheilkunde. Die Ophthalmol. 2025;122:2–3.

2025

Bock R, Roth M, Geerling G. Mycotic Keratitis – Signs, Diagnosis, Therapy. Klin Monatsbl Augenheilkd. 2025;242:636–642.

2025

Holtmann C, et al. Orbital Floor Fractures in Germany: Interdisciplinary Care without a Uniform Standard – Results of a Multicentre Survey. Klin Monatsbl Augenheilkd. 2025;242:927–934.

2025

Heinz C, et al. Prospektives internationales Register für Treatment Exit Options in Uveitis (TOFU) – die ersten 5 Jahre. Klin Monatsbl Augenheilkd. 2025. doi: 10.1055/a-2529-0057

2025

Roth M, Geerling G, Strzalkowski P, Lindhof HH, Guthoff R. „Neue“ Erreger okulärer Infektionen durch Umweltveränderungen – Was kommt auf uns zu? Die Ophthalmol. 2025;122:31–36.

2024

Strzalkowski P, et al. Evaluation of the accuracy and readability of ChatGPT-4 and Google Gemini in providing information on retinal detachment: a multicenter expert comparative study. Int J Retin Vitr. 2024;10:61.

2024

Roth M, Yaïci R, Borrelli M, Geerling G. Mucous Membrane Pemphigoid with Ocular Involvement. In: Atlas on Cornea: Diagnostics, Diseases and Therapies. Springer; 2025. p. 559–572. https://doi.org/10.1007/978-3-031-65422-0_31

2024

Yaïci, R. et al. ChatGPT und die deutsche Facharztprüfung für Augenheilkunde: eine Evaluierung. Die Ophthalmol. 1–10 (2024) doi:10.1007/s00347-024-02046-0.

2024

Schilcher, A. V., Roth, M., Steindor, F. A., Helweh, R. & Geerling, G. “Dirty Dry Eye”– A waste volume analysis from topical therapy in keratoconjunctivitis sicca. Graefe’s Arch. Clin. Exp. Ophthalmol. 1–8 (2024) doi:10.1007/s00417-024-06431-y.

2024

Huth A, Roth M, Viestenz A. Endogene Candida-Endophthalmitis. Die Ophthalmol. 2024;1–9.

2023

Roth, M. & Geerling, G. Die Augenheilkunde, Das Referenzwerk. *Springer Ref. Med.* 1–11 (2023) doi:10.1007/978-3-662-65929-8_138-1.

2023

Roth, M., Schröder, K., Borgardts, K. C., Pleyer, U. & Geerling, G. Die Augenheilkunde, Das Referenzwerk. *Springer Ref. Med.* 1–8 (2023) doi:10.1007/978-3-662-65929-8_139-1.

2023

Borgardts, K. C., Roth, M. & Geerling, G. Die Augenheilkunde, Das Referenzwerk. *Springer Ref. Med.* 1–13 (2023) doi:10.1007/978-3-662-65929-8_137-1.

2023

Wespiser S, Koestel E, (…), SMIK study group (Roth M et al.), Bourcier T. Practice patterns in the management of bacterial keratitis: a five-continent survey. Graefe’s Archive Clin Exp Ophthalmol. 2023;1–9.

2023

Roth M, Fangerau H, Geerling G. Okuläres Pemphigoid – Neue Erkenntnisse zu einem uralten Krankheitsbild. Die Ophthalmol. 2023;120(5):460–1.

2023

Yaïci R, Roth M, Geerling G. Erste Ergebnisse des Deutschen okulären Pemphigoid-Registers. Die Ophthalmol. 2023;1–6. doi: 10.1007/s00347-023-01859-9

2023

Geerling G, Yaici R, Roth M. Therapie des okulären Schleimhautpemphigoids. Die Ophthalmol. 2023;1–5. doi: 10.1007/s00347-023-01869-7

2023

Roth M, Balasiu A, Daas L, Holtmann C, Servera A, Walckling M, Mackenzie CR, Fuchsluger TA, Geerling G. Impact of implementation of polymerase chain reaction on diagnosis, treatment, and clinical course of Acanthamoeba keratitis. Graefe’s Archive Clin Exp Ophthalmol. 2023. https://doi.org/10.1007/s00417-023-05993-7

2023

Roth M, Yaici R, Geerling G. Klinik des okulären Schleimhautpemphigoids. Die Ophthalmol. 2023;1–5. doi: 10.1007/s00347-023-01854-0

2023

Hofmann SC, Günther C, Böckle BC, Didona D, Ehrchen J, Gaskins M, (…) Roth M et al. S2k‐Leitlinie zur Diagnostik und Therapie des Schleimhautpemphigoids. Jddg J Der Deutschen Dermatologischen Gesellschaft. 2022;20(11):1530–52.

2023

(DOG) DOG, Geerling G, Birtel J, Faber H, Fangerau H, Gamulescu A, (…) Roth M et al. Positionspapier und Handlungsempfehlungen für eine ökologisch nachhaltige Augenheilkunde. Die Ophthalmol. 2023;120(1):52–68.

2022

Borrelli M, Witt J, Roth M, Reichl S, Bradenbrink P, Schoppe M, et al. Keratin films for ocular surface reconstruction: Wound healing in an in-vivo model. Exp Eye Res. 2022;109356.

2022

Holtmann C, Roth M, Filler T, Bergmann AK, Hänggi D, Muhammad S, et al. Microvascular anastomosis of the human lacrimal gland: a concept study towards transplantation of the human lacrimal gland. Graefe’s Archive Clin Exp Ophthalmol. 2022;1–8.

2022

Holtmann C, Roth M, Lanzman RS, Turowski B, Antoch G, Mackenzie CR, et al. Diagnostik und Therapie organischer intraorbitaler Fremdkörper. Die Ophthalmol. 2022;1–6.

2022

Roth M, Holtmann C, Daas L, Kakkassery V, Kurzai O, Geerling G, et al. Results From the German Fungal Keratitis Registry: Significant Differences Between Cases With and Without a History of Contact Lens Use. Cornea. 2021;40(11):1453–61.

2022

Yaïci R, Roth M, Juergens L, Nawaiseh SA, Burkhard D, Besgen V, et al. Zur Versorgungssituation und konservativen Therapie des okulären vernarbenden Schleimhautpemphigoids in Deutschland. Klinische Monatsblätter Für Augenheilkunde. 2022;

2022

Roth M, Goerke P, Holtmann C, Frings A, MacKenzie CR, Geerling G. Spectrum and resistance in bacterial infections of the ocular surface in a German tertiary referral center 2009–2019. Graefe’s Archive Clin Exp Ophthalmol. 2022;1–9.

2022

Sourlis C, Seitz B, Roth M, Hamon L, Daas L. Outcomes of Severe Fungal Keratitis Using in vivo Confocal Microscopy and Early Therapeutic Penetrating Keratoplasty. Clin Ophthalmol. 2022;Volume 16:2245–54.

2022

Jürgens L, Yaici R, Schnitzler CM, Fleitmann AK, Roth M, Schröder K, et al. Retinal vascular occlusion in pregnancy: three case reports and a review of the literature. J Medical Case Reports. 2022;16(1):167.

2022

Kourukmas R, Roth M, Geerling G. Automated vs. human evaluation of corneal staining. Graefe’s Archive Clin Exp Ophthalmol. 2022;1–8.

2022

Roth M, Herrmann ME, Geerling G, Guthoff R. Aktuelle und zukünftige Auswirkungen des Klimawandels auf die Augenheilkunde. Der Ophthalmol. 2022;1–7.

2022

Roth M, Dierse S, Alder J, Holtmann C, Geerling G. Incidence, prevalence, and outcome of moderate to severe neurotrophic keratopathy in a German tertiary referral center from 2013 to 2017. Graefe’s Archive Clin Exp Ophthalmol. 2022;1–13.

2021

Yaici R, Balasiu A, Mackenzie CR, Roth M et al (2021) Ocular Syphilis : Experience over 11 Years at a German Ophthalmology Reference Centre Ocular Syphilis : Experience over 11 Years at a German Ophthalmology Reference. Ocul Immunol Inflamm 00:1–7. https://doi.org/10.1080/09273948.2021.1998547

2021

Roth M, Schön N, Jürgens L, et al (2021) Frequently assessed and used prognostic factors for outcome after macular hole surgery : which is better ? BMC Ophthalmol 1–11. https://doi.org/10.1186/s12886-021-02164-2

2021

Roth M, Holtmann C, Daas L, Kakkassery V et al. Results From the German Fungal KeratitisRegistry - Significant Differences Between Cases With and Without a History of Contact Lens Use; June 2021, Cornea doi: 10.1097/ICO.0000000000002705

2021

Schmidt E, Rashid H, Marzano AV, Lamberts A, Di Zenzo G, Diercks GFH, Roth M et al. European Guidelines (S3) on diagnosis and management of mucous membrane pemphigoid, initiated by the European Academy of Dermatology and Venereology – Part II. J Eur Acad Dermatology Venereol. 2021;

2021

Walther G, Zimmermann A, Theuersbacher J, Kaerger K, Lilienfeld-toal M Von, Roth M, et al. Eye Infections Caused by Filamentous Fungi : Spectrum and Antifungal Susceptibility of the Prevailing Agents in Germany. 2021;

2021

Rashid H, Lamberts A, Borradori L, Alberti-Violetti S, Barry RJ, Caproni M, Roth M et al. European guidelines (S3) on diagnosis and management of mucous membrane pemphigoid, initiated by the European Academy of Dermatology and Venereology – Part I. J Eur Acad Dermatology Venereol. 2021;

2020

Steindor F, Borrelli M, Duarte E, Roth M, Holtmann C, Menzel-Severing J, et al. Das deutsche Klinikpartnerschaftsprogramm am Beispiel der Kooperation der Klinik für Augenheilkunde des Universitätsklinikums Düsseldorf mit der Fundación Visión in Asunción ( Paraguay ). Der Ophthalmol. 2020;

2020

Roth M, Steindor F, Kurzai O, Mackenzie CR, Geerling G. Mykotische Keratitis: Klinische Zeichen, Diagnose, Therapie. Augenheilkd up2date. 2020;10:8. – 16.

2020

Roth M, Daas L, MacKenzie CR, Balasiu A, Stachon T, Neumann I, et al. Development and Assessment of a Simulator for in Vivo Confocal Microscopy in Fungal and Acanthamoeba Keratitis. Curr Eye Res [Internet]. 2020;45(12):1484–9. Available from: https://doi.org/10.1080/02713683.2020.1772830

2019

Dietrich J, Roth M, König S, Geerling G, Mertsch S, Schrader S. Analysis of lacrimal gland derived mesenchymal stem cell secretome and its impact on epithelial cell survival. Stem Cell Res [Internet]. 2019;38(January):101477. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1873506119301072

2019

Borgardts K, Frings A, Roth M, Geerling G, Schargus M. Konjunktivitiden als Ursache eines roten Auges. Z. prakt. Augenheilkd. 2019; 40:25-40

2019

Dietrich J, Ott L, Roth M, Witt J, Geerling G, Mertsch S, et al. MSC Transplantation Improves Lacrimal Gland Regeneration after Surgically Induced Dry Eye Disease in Mice. Sci Rep-uk. 2019;9(1):18299.

2019

Roth M, Holtmann C, Böhringer D, Finger RP, Eter N, Seitz B, et al. Stand und Perspektiven registerbasierter Studien in der deutschen Augenheilkunde. [Status and perspectives of registry-based studies in German ophthalmology]. Der Ophthalmol. 2019;117(1):36–43.

2019

Roth M, Daas L, Renner-Wilde A, Cvetkova-Fischer N, Saeger M, Herwig-Carl M, et al. Das Deutsche Pilz-Keratitis- Register Erste Ergebnisse einer multizentrischen Erhebung [The German keratomycosis registry. Initial results of amulticenter survey]. Der Ophthalmol [Internet]. 2019;116. Available from: http://link.springer.com/10.1007/s00347-019-0871-9

2019

Borgardts K, Frings A, Roth M, Geerling G, Schargus M. Teil 2 : Nichtinfektiöse Konjuntivitiden Konjunktivitiden als Ursache eines roten Auges. Z. prakt. Augenheilkd. 2019;100:85–100.

2019

Geerling G, Roth M. Pseudopemphigoid bei topischer Glaukomtherapie Pseudopemphigoid Induced by Topical Glaucoma Medications Einleitung Definition – Schleimhautpemphigoid Differenzialdiagnostik von Schleimhaut-. 2019;762–6.

2018

Dietrich J, Schlegel C, Roth M, Witt J, Geerling G, Mertsch S, et al. Comparative analysis on the dynamic of lacrimal gland damage and regeneration after Interleukin-1α or duct ligation induced dry eye disease in mice. Exp Eye Res [Internet]. 2018;172(December 2017):66–77. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0014483517308369

2018

Roth M, Eisenkopf L, Engineer D, Schmidt JC. Lasermembranotomie beim Management einer akuten prämakulären Blutung. Der Ophthalmol [Internet]. 2018;115(12):1059–65. Available from: http://link.springer.com/10.1007/s00347-018-0692-2

2017

Habbe KJ, Frings A, Schrader S, Roth M, MacKenzie C, Walther G, et al. Tintelnotia destructans: Ein neuer Feind vor dem Tore. Ophthalmologe [Internet]. 2017;5–7. http://link.springer.com/10.1007/s00347-017-0641-5

2017

Roth M., Frings A., Daas L., Seitz B., Saeger M., Cvetkova N., Herwig-Carl M. C., Fischer C. V., Kroll S., Enders P., Mehlan J., Stasch S., Walther G., MacKenzie C., Schrader S., von Lilienfeld-Toal M.,Kurzai O., Geerling G. (2017) Das Deutsche Pilzkeratitis-Register – ein Zwischenbericht. Der Ophthalmologe, 114 (Suppl2): 79 DOI 10.1007/s00347-017-0551-6

2017

Walther, G., Stasch, S., Kaerger, K., Hamprecht, A., Roth, M., Cornely, O., Geerling, G.,Mackenzie, C., Kurzai, O., von Lilienfeld-Toal, M. (2017) Eye infections caused by Fusarium spp. - a two year experience from the National Reference Centre for Invasive Mycoses (NRZMyk) Jena. Journal of Clinical Microbiology 55:2983–2995. https://doi.org/10 .1128/JCM.00649-17.

2016

11. Roth, M., Holtmann, C., Borrelli M., Kajasi N., MacKenzie, C., Geerling G. (2016) Periokuläre nekrotisierende Fasziitis - Überblick und Fallbericht. Klinische Monatsblätter Für Augenheilkunde 234(1):40–45. http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-119300

2015

Daas, L., Szentmáry, N., Eppig, T., Langenbucher, A., Hasenfus, A., Roth, M., et al. (2015). [The German Acanthamoeba keratitis register : Initial results of a multicenter study]. Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft, 1–11. http://doi.org/10.1007/s00347-014-3225-7

2015

Holtmann, C., Brachert, M., Spaniol, K., Roth, M., Cacchi, C., & Geerling, G. (2015). [Dacryolith in a lacrimal duct]. Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft, 1–3. http://doi.org/10.1007/s00347-015-0085-8

2015

Roth, M., Schrader, S., Finis, D., Spaniol, K., MacKenzie, C., Ackermann, P., & Geerling, G. (2015). [Diagnostics of Infectious Corneal and Conjunctival Diseases]. Klinische Monatsblätter Für Augenheilkunde, (EFirst). http://doi.org/10.1055/s-0033-135813

2015

Behrens-Baumann, W., Finis, D., MacKenzie, C., Roth, M., & Geerling, G. (2015). [Keratomycosis - Therapy Standards and New Developments]. Klinische Monatsblätter Für Augenheilkunde, 232(6), 754–764. http://doi.org/10.1055/s-0035-1546032

2015

Roth, M., Spaniol, K., Kordes, C., Schwarz, S., Mertsch, S., Häussinger, D., et al. (2015). The Influence of Oxygen on the Proliferative Capacity and Differentiation Potential of Lacrimal Gland-Derived Mesenchymal Stem Cells. Investigative Ophthalmology & Visual Science, 56(8), 4741–4752. http://doi.org/10.1167/iovs.14-15475

2015

Spaniol, K., Metzger, M., Roth, M., Greve, B., Mertsch, S., Geerling, G., & Schrader, S. (2015). Engineering of a secretory active three-dimensional lacrimal gland construct on the basis of decellularized lacrimal gland tissue. Tissue Engineering. Part A, 150729113407005. http://doi.org/10.1089/ten.TEA.2014.0694

2015

Dietrich, J., Massie, I., Roth, M., Geerling, G., Schrader, S. (2015). Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy. Part 1: Regeneration of Lacrimal Gland Tissue: Can We Stimulate Lacrimal Gland Renewal In Vivo? Current Eye Research Current Eye Research, 1–12. http://doi.org/10.3109/02713683.2016.1148741

2015

Massie, I., Dietrich, J., Roth, M., Geerling, G., Schrader, S. (2015). Development of Causative Treatment Strategies for Lacrimal Gland Insufficiency by Tissue Engineering and Cell Therapy. Part 2: Reconstruction of Lacrimal Gland Tissue: What Has Been Achieved So Far And What Are The Remaining Challenges? Current Eye Research, 1–11. http://doi.org/10.3109/02713683.2016.1151531

2014

Spaniol, K., Roth, M., & Stupp, T. (2014). [Acute alteration of corneal topography]. Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft, 111(7), 672–675. http://doi.org/10.1007/s00347-013-2998-4

2014

Schrader, S., Finis, D., Spaniol, K., Roth, M., Ackermann, P., & Geerling, G. (2014). [Clinical diagnostics for the tear film and the ocular surface]. Klinische Monatsblätter Für Augenheilkunde, 231(9), 937–939–47– quiz 948–50. http://doi.org/10.1055/s-0033-1357966