Unsere Augenärzte

Prof. Dr. Dr. Theo Seiler,
YOUSEE Gründer &
Augenlaser-Pionier

Porträt des Erfinders des Augenlaserns Professor Dr. Dr. Theo Seiler

Innovation für besseres Sehen:
Von der ersten PRK bis zum Crosslinking

Prof. Dr. Dr. Theo Seiler gilt als Pionier der modernen Augenlaser- und Hornhautchirurgie.
Er entwickelte 1983 den ersten klinischen Farbstofflaser und 1984 neuartige Oberflächenspulen für die Magnetresonanztomographie der Augenhöhle. 1985 führte er die weltweit erste phototherapeutische Keratektomie (PTK) am menschlichen Auge durch, 1987 folgte die erste photorefraktive Keratektomie (PRK), 1988 die erste Holmium-YAG-Laser-Thermokeratoplastik und 1989 die ersten klinischen Studien zu PRK.

1995 erfand Prof. Dr. Dr. Seiler das corneale Crosslinking (CXL), das 1998 erstmals klinisch angewendet wurde und heute als Standardverfahren zur Stabilisierung der Hornhaut gilt.
1999 führte er die erste wellenfrontgeführte Augenlaser-Behandlung weltweit durch, 2002 folgte die erste topographiegesteuerte Laserbehandlung mit dem WaveLight-Laser.
2010 kombinierte er erstmals LASIK mit rapid Crosslinking, um die Behandlungsmöglichkeiten weiter zu verbessern.

Vom Physiker zum Pionier
der refraktiven Augenchirurgie

Prof. Dr. Dr. Theo Seiler studierte zunächst Mathematik und Physik, bevor er Medizin an der Freien Universität Berlin abschloss. Dort promovierte er sowohl in Physik (1975) als auch in Medizin (1984, summa cum laude) und habilitierte sich 1987 mit Arbeiten zur refraktiven Hornhautchirurgie. Nach Stationen als Oberarzt und Professor an der FU Berlin leitete er ab 1993 die Augenklinik des Universitätsklinikums Dresden und wechselte 2000 als Direktor an die Augenklinik der Universität Zürich.

2002 gründete er in Zürich das Institut für Refraktive und Ophthalmo-Chirurgie (IROC), in dem er bis heute innovative Verfahren der refraktiven- und Hornhaut-Chirurgie sowie der physiologischen Optik entwickelt und erforscht.

Werdegang

2018

Gründung der YOUSEEZÜRI AG und der YOUSEECLINICS Gruppe

2002

Gründung des Instituts für Refraktäre und Ophthalmo-Chirurgie (IROC)

2000-2002

Professor und Direktor an der Augenklinik im Universitätsspital Zürich

1993

Professor und Direktor an der Augenklinik der Technischen Universität Dresden

1990

Professor für Ophthalmologie an der Freien Universität Berlin

1985-1990

Oberarzt und Privatdozent an der Augenklinik der Freien Universität Berlin

1980-1985

Assistenzarzt und Promotion an der Augenklinik der Freien Universität Berlin

1975-1980

Oberstudienrat am Peter-A.-Silbermann- Kollegium Berlin und akademischer Rat an der Freien Universität Berlin

1974

Promotion in Experimentalphysik an der Freien Universität Berlin

Auszeichnungen

2023

Hall of Fame (The Ophthalmologist)

2023

Castroviejo lecture (AAO)

2020

Heritage lecture (ESCRS)

2018

Innovators lecture (DOC)

2017

Presidential Recognition Award (ISRS)

2014

Most influential ophthalmologist (The Ophthalmologist)

2014

Hall of Fame (ASCRS)

2012

International Leadership in Ophthalmology (HOF)

2012

Key note lecture for Claes Dohlman (AAO)

2010

Science Award (DGII)

2009

Senior Achievement Award (AAO)

2008

Innovators lecture (ASCRS)

2004

Lifetime Achievement Award (AAO)

2002

President’s Award (ISRS/ AAO)

1997

Honour Award (AAO)

1996

Graefe Award (DOG)

1995

Barraquer Award (AAO)

1994

Binkhorst Award (AAO)

1994

Khing Khaled-Award (SAOS)

1987

Axenfeld-Award (DOG)

Premieren

2016

Erstes individuelles CXL

2014

Erste OCT-geführte Femtosekundenlaser-DALK

2010

Erstes Flashlinking bei LASIK

2008

Erste Behandlungen mit dem Femtosekunden-WaveLight-Laser

2002

Erste topografiegeführte Behandlung mit einem WaveLight-Laser

1999

Weltweit erste wellenfrontgeführte Behandlung

1998

Erste klinische Anwendung von CXL

1995

Erfindung des Corneal- und Scleral-Crosslinkings

1989

Erste prospektive klinische Studie zur Excimer-Laser-PRK

1988

Weltweit erste Holmium:YAG-Laser-Keratoplastik

1986

Weltweit erste Augenlaser-Operation am Menschen via Excimer-Laser-PRK

1985

Weltweit erste Augenlaser-Operation am Menschen via Excimer-Laser-PTK

1984

Entwicklung der ersten Oberflächen-Spulen für die MRT der Augenhöhle

1983

Entwicklung des ersten Farbstofflasers für die klinische Augenheilkunde

Professor Dr. Dr. Theo Seiler erhält die Castroviejo Medal der American Academy of Ophthalmology (AAO).
Diese Auszeichnung wird für herausragende Beiträge in der Hornhaut- und vorderen Augensegmentforschung verliehen.

In seiner umfangreichen Auszeichnungsliste finden sich viele renommierte Preise der AAO, wie der Honour Award (1997), President's Award (2002), Lifetime Achievement Award (2004) und Senior Achievement Award (2009).

Augenlaser-Pionier & Gründer Prof. Dr. Dr. Theo Seiler erhält die Castroviejo Medal der American Academy of Ophthalmology (AAO).

Die American Academy of Ophthalmology (AAO) ist mit über 32.000
Mitgliedern die weltweit größte Fachgesellschaft für Augenärzte.

Die AAO setzt international Standards in der augenärztlichen
Weiterbildung, medizinischen Forschung und Betreuung,
fördert die öffentliche Aufklärung zur Augengesundheit und bietet
zahlreiche Ressourcen für Fachleute und Patienten weltweit an.

Publikationen
Anzahl der Publikationen: 146

1982

Graefes Arch Clin Exp Ophthalmol: "The distinction of corneal water in free and bound fractions"

1983

Graefes Arch Clin Exp Ophthalmol: "Phase transitions in ocular tissue - NMR and temperature measurements"

1983

Graefes Arch Clin Exp Ophthalmol: "Nuclear spin tomography of the human eye"

1984

Fortschr Ophthalmol: "Outflow resistance in the trabecular meshwork"

1984

Fortschr Ophthalmol: "Late results in eye contusions"

1984

Fortschr Ophthalmol: "Early operative recuperation phase of the retina following vitreous surgical interventions--an animal experiment model"

1985

Graefes Arch Clin Exp Ophthalmol: "The resistance of the trabecular meshwork to aqueous humor outflow"

1985

Fortschr Ophthalmol: "The Berlin dye laser"

1985

Fortschr Ophthalmol: "NMR tomography of the eye"

1985

Fortschr Ophthalmol: "Endothelial cell defects caused by ultrasound phacoemulsification in a model"

1985

Fortschr Ophthalmol: "Behavior of astigmatism following IOL implantation"

1986

Fortschr Ophthalmol: "Use of far UV light in photoablation of the cornea"

1986

Ophthalmologica: "NMR-tomography of the human eye"

1986

Ophthalmologica: "In vivo experiments with the excimer laser--technical parameters and healing processes"

1987

Fortschr Ophthalmol: "Transparency of the cornea"

1987

Fortschr Ophthalmol: "New findings in keratoconus"

1987

Fortschr Ophthalmol: "Laser surgery of the cornea"

1988

Graefes Arch Clin Exp Ophthalmol: "Side effects in excimer corneal surgery. DNA damage as a result of 193 nm excimer laser radiation"

1988

Graefes Arch Clin Exp Ophthalmol: "Side effects in excimer corneal surgery. Corneal thermal gradients"

1988

Fortschr Ophthalmol: "Magnetic resonance tomography of choroid melanoma"

1988

Fortschr Ophthalmol: "Goniotrepanation with an inverse-folded flap"

1989

Fortschr Ophthalmol: "Visual evoked cortical potentials modified by a NMR magnetic field of 0.24 Tesla"

1989

Fortschr Ophthalmol: "Superficial ablation of the cornea using the excimer laser (193 nm)"

1989

Fortschr Ophthalmol: "Magnetic resonance tomography in ophthalmologic diagnosis"

1989

Fortschr Ophthalmol: "Amelanotic melanoma and nuclear magnetic resonance tomography--case report"

1990

Biomed Tech (Berl): "Laser coagulation with the Ho:YAG laser"

1990

Fortschr Ophthalmol: "The ablation behavior of various corneal layers"

1990

Biomed Tech (Berl): "Principles of refractive corneal surgery with the 193 nm Excimer laser"

1990

Fortschr Ophthalmol: "Laser surgery of the cornea"

1990

Fortschr Ophthalmol: "Laser keratomileusis for correction of myopia"

1990

Biomed Tech (Berl): "Calibration of the 193 nm Excimer laser beam"

1990

Biomed Tech (Berl): "Auto-tuning unit for low-field NMR tomography equipment"

1991

Fortschr Ophthalmol: "Wound healing of the cornea of New World monkeys after surface keratectomy: Er:YAG-excimer laser"

1991

Fortschr Ophthalmol: "Photoablation with the Er:YAG laser in ocular tissues"

1991

Fortschr Ophthalmol: "Laser coagulation of the cornea with a holmium:YAG laser for correction of hyperopia"

1992

Ger J Ophthalmol: "Pterygium excision using 193-nm excimer laser smoothing and topical mitomycin C"

1992

Ger J Ophthalmol: "Pseudoexfoliation syndrome and glaucoma. Does glaucoma capsulare exist?"

1992

Ger J Ophthalmol: "Diurnal variation in refraction after excimer laser photorefractive keratectomy"

1993

J Cataract Refract Surg: "Effective spherical aberration of the cornea as a quantitative descriptor in corneal topography"

1996

Ophthalmic Res: "Laser Scheimpflug videography"

1997

Int Ophthalmol: "Unilateral Meesmann's dystrophy"

1998

Duncker GIW et al. (Hrsg), 12. Kongress der Deutschsprachigen Gesellschaft für Intraokularlinsen-Implantation und Refraktive Chirurgie. Springer, Berlin Heidelberg, pp. 303-311: "Frühkindliche Hornhauthauttrübungen als Ursache einer Formdeprivationsmyopie (FDM)"

1998

Biomed Tech (Berl): "Practical technical measurement problems in determining optical image errors of the human eye with a video-aberroscope"

1998

Biomed Tech (Berl): "Determining the position of distorted point lattice patterns on the human retina by evaluating monochromatic image errors"

1999

Ophthalmic Res Scheimpflug records without distortion--a mythos?

1999

Front Radiat Ther Oncol: "Effects of high-dose radiotherapy to tumors of the pituitary on the optic chiasm"

2000

Technol Health Care: "Transpupillary laser phototherapy of tumors and vascular anomalies of retina and choroid: theoretical approach and clinical implications"

2000

Arch Ophthalmol: "Ocular optical aberrations after photorefractive keratectomy for myopia and myopic astigmatism"

2000

J Refract Surg: "Limitations of erbium:YAG laser photorefractive keratectomy"

2000

J Refract Surg: "Wavefront-guided laser in situ keratomileusis: early results in three eyes"

2000

Ophthalmologe: "Studies on the stabilization of the cornea in rabbits"

2000

Ophthalmologe: "Erbium:YAG laser vitrectomy: temperature measurements in different replacement materials"

2000

Ophthalmology: "Comparison of erbium:yttrium-aluminum-garnet-laser vitrectomy and mechanical vitrectomy: a clinical study"

2000

J Cataract Refract Surg: "Refractive surgical problem"

2000

J Refract Surg: "Principles of Tscherning aberrometry"

2000

J Refract Surg: "Operative correction of ocular aberrations to improve visual acuity"

2000

Ophthalmologe: "Motion artifacts in the vitreous body during vitrectomy"

2000

Klin Monbl Augenheilkd: "Irradiation of cornea with ultraviolet light and riboflavin administration as a new treatment for erosive corneal processes, preliminary results in four patients"

2000

J Refract Surg: "Clinical experience with the Tscherning aberrometer"

2000

Graefes Arch Clin Exp Ophthalmol: "Manifest diabetes and keratoconus: a retrospective case-control study"

2001

J Cataract Refract Surg: "Clinical results of wavefront-guided laser in situ keratomileusis 3 months after surgery"

2001

Ophthalmologe: "Cavitation bubble formation during Erbium:YAG laser vitrectomy"

2001

J Cataract Refract Surg: "Increased higher-order optical aberrations after laser refractive surgery: a problem of subclinical decentration"

2001

Ophthalmology: "Understanding refraction and accommodation through "retinal imaging" aberrometry: a case report"

2001

Klinische Monatsblätter für Augenheilkunde: "Supportive amblyopia treatment by means of computer games with background stimulation"

2001

J Biomed Opt: "Ocular optical aberrometer for clinical use"

2001

Ophthalmology: "Stress wave amplitudes during laser surgery of the cornea"

2001

Praxis (Bern 1994): Does refractive surgery really make eyeglasses superfluous?

2001

Ophthalmologe: "Ultrasound biomicroscopy diagnosis of traumatic choroid effusion without cyclodialysis"

2001

J Cataract Refract Surg: "Improvement in photorefractive corneal laser surgery results using an active eye-tracking system"

2001

J Biomed Opt: "Erbium: yttrium-aluminum-garnet laser induced vapor bubbles as a function of the quartz fiber tip geometry"

2001

Ophthalmologe: "Fundamentals of wavefront-guided refractive corneal surgery"

2001

Ophthalmologe: "Change of paradigms in refractive surgery"

2001

J Refract Surg: "Influence of corneal curvature on calculation of ablation patterns used in photorefractive laser surgery"

2002

Jpn J Ophthalmol: "Corneal myxoma"

2002

Ophthalmology: "Optical low coherence reflectometry for noncontact measurements of flap thickness during laser in situ keratomileusis"

2002

J Refract Surg: "Aberration-sensing and wavefront-guided laser in situ keratomileusis: management of decentered ablation"

2002

Curr Opin Ophthalmol: "Customized corneal ablation"

2002

J Refract Surg: "Experimental results of preparing laser-shaped stromal implants for laser-assisted intrastromal keratophakia in extremely complicated laser in situ keratomileusis cases"

2003

Ophthalmologe: "Treatment of keratoconus by collagen cross linking"

2003

Eur J Ophthalmol: "Multicenter evaluation of tendency-oriented perimetry (TOP) using the G1 grid"

2003

J Refract Surg "Anterior lamellar keratoplasty with a microkeratome: a method for managing complications after refractive surgery"

2003

J Cataract Refract Surg: "Maximum permissible lateral decentration in aberration-sensing and wavefront-guided corneal ablation"

2003

J Refract Surg: "Correlation between corneal and total wavefront aberrations in myopic eyes"

2003

Am J Ophthalmol: "Riboflavin/ ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus"

2003

J Cataract Refract Surg: "Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking"

2003

J Cataract Refract Surg: "Endothelial cell damage after riboflavin-ultraviolet-A treatment in the rabbit"

2004

J Cataract Refract Surg: "Maximum permissible torsional misalignment in aberration-sensing and wavefront-guided corneal ablation"

2004

J Refract Surg: "Laser intrastromal keratoplasty--case report"

2004

Cornea: "Keratocyte apoptosis after corneal collagen cross-linking using riboflavin/UVA treatment"

2004

Ophthalmologica: "Thermomechanical behavior of collagen-cross-linked porcine cornea"

2004

Eye (Lond): "Keratocyte cytotoxicity of riboflavin/UVA-treatment in vitro"

2004

Curr Eye Res: "Increased resistance of crosslinked cornea against enzymatic digestion"

2004

Cornea: "Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin/UVA"

2004

J Refract Surg: "Transferring wavefront measurements into corneal ablations: an overview of related topics"

2005

Klin Monbl Augenheilkd: "latrogenic corneal ectasia after LASIK--is the end in sight?"

2005

Eur J Ophthalmol: "Dependence of wave front refraction on pupil size due to the presence of higher order aberrations"

2005

J Cataract Refract Surg: "Two-step procedure to enlarge small optical zones after photorefractive keratectomy for high myopia"

2005

Klin Monbl Augenheilkd: "Asphericity of the cornea and astigmatism"

2006

Ophthalmologe: "Ablation profiles in corneal laser surgery. Current and future concepts"

2006

J Cataract Refract Surg: "Q-factor customized ablation profile for the correction of myopic astigmatism"

2006

Ophthalmologe: "Nomograms for the improvement of refractive outcomes"

2006

J Refract Surg: "The effect of phenylephrine and cyclopentolate on objective wavefront measurements"

2006

J Cataract Refract Surg: "Customized ablation algorithm for the treatment of steep central islands after refractive laser surgery"

2006

J Cataract Refract Surg: "Corneal and total wavefront aberrations in phakic and pseudophakic eyes after implantation of monofocal foldable intraocular lenses"

2006

Klin Monbl Augenheilkd: "Reoperations after LASIK"

2006

Cornea: "Corneal cross-linking-induced stromal demarcation line"

2006

Ophthalmology: "Topography-guided surface ablation for forme fruste keratoconus"

2006

J Cataract Refract Surg: "Four corneal presbyopia corrections: simulations of optical consequences on retinal image quality"

2007

Cornea: "Safety of UVA-riboflavin cross-linking of the cornea"

2007

Klin Monbl Augenheilkd: "Therapeutic cross-linking of the cornea using riboflavin/UVA"

2007

J Cataract Refract Surg: "Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis"

2008

J Refract Surg: "Optical ray tracing for the calculation of optimized corneal ablation profiles in refractive treatment planning"

2008

Cornea: "Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts"

2008

J Refract Surg: "Efficacy and safety of blue-light scleral cross-linking"

2009

Ophthalmology: "Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking"

2009

J Cataract Refract Surg: "Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas"

2009

J Cataract Refract Surg: "Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas"

2009

J Cataract Refract Surg: "Complication and failure rates after corneal crosslinking"

2009

Arch Ophthalmol: "Intraoperative and postoperative effects of corneal collagen cross-linking on progressive keratoconus"

2010

J Refract Surg: "Persistent subepithelial haze in thin-flap LASIK"

2010

Ophthalmology: "Light-adjustable lens complication"

2010

J Refract Surg: "Corneal infiltrates after corneal collagen cross-linking"

2010

J Refract Surg: "Technical aspects of the WaveLight FS200 femtosecond laser"

2011

J Refract Surg: "Laboratory measurement of the absorption coefficient of riboflavin for ultraviolet light (365 nm)"

2011

Br J Ophthalmol: "Marked remodelling of the anterior corneal surface following collagen cross-linking with riboflavin and UVA"

2011

J Cataract Refract Surg: "Flattening of the cornea after collagen crosslinking for keratoconus"

2011

J Refract Surg: "Bilateral ring-shaped intrastromal opacities after corneal cross-linking for keratoconus"

2012

PLoS One: "Evaluation of the efficacy of excimer laser ablation of cross-linked porcine cornea"

2012

J Cataract Refract Surg: "Optical ray tracing-guided laser in situ keratomileusis for moderate to high myopic astigmatism"

2012

Invest Ophthalmol Vis Sci: "Optimization model for UV-riboflavin corneal cross-linking"

2012

J Refract Surg: "Pregnancy may trigger late onset of keratectasia after LASIK"

2013

Cornea: "Riboflavin/ultraviolet a crosslinking of the paracentral cornea"

2013

Indian J Ophthalmol: "The paradigm change in keratoconus therapy"

2013

PLoS One: "Progranulin is a novel independent predictor of disease progression and overall survival in chronic lymphocytic leukemia"

2014

Ophthalmologe: "Innovations in refractive laser surgery 2014"

2015

J Cataract Refract Surg: "Corneal tissue interactions of a new 345 nm ultraviolet femtosecond laser"

2017

Klin Monbl Augenheilkd: "Limitations of SMILE (Small Incision Lenticule Extraction)"

2017

J Cataract Refract Surg: "Wound healing in rabbit corneas after flapless refractive lenticule extraction with a 345 nm ultraviolet femtosecond laser"

2018

J Cataract Refract Surg: "Interface morphology and gas production by a refractive 347 nm ultraviolet femtosecond laser: Comparison with established laser systems"

2019

Klin Monbl Augenheilkd: "Bacterial and Fungal Keratitis: A Retrospective Analysis at a University Hospital in Switzerland"

2019

Cornea: "Intraoperative Optical Coherence Tomography-Guided Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty"

2019

J Cataract Refract Surg: "Corneal crosslinking without epithelial removal"

2021

J Cataract Refract Surg: "Keratoconus and corneal crosslinking"

2022

J Clin Med: "Early Experience with the Biotronik Protego ICD Lead"

2022

J Refract Surg: "Lenticule Extraction"

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